Calcluation of Matsuda Index

Use the following form below to calculate Matsuda Index from one set of OGTT data.

To access EXCEL file please click here.

If you have samples from 0, 30, 60, 90 and 120 minutes. Click here.
If you have samples from 0, 30, 60, and 120 minutes. Click here.
If you have samples from 0, 60, and 120 minutes. Click here.
If you have samples from 0 and 120 minutes Click here.
If you have samples from 0, 30 and 120 minutes Click here.

Please use as many as possible measurements to calculate the AUC (area under the curve) of responses of glucose and insulin, preferably until the return to the basal state (i.e., up to 180 or 240 minutes), although this site does not support the calculation. Matsuda index uses the metabolic clearance rate during the OGTT. Option of different doses other than 75 g of glucose has not been well validated. Use the same way of calculation for comparison.

Click after data input

Dose [g] (usually 75g) :
When you use a SGLT-2 inhibitor, examine urine excretion and subtract from 75(g) and input it to the upper box!
Or use corrected values obtained from urine glucose excretion in Diabetes Care 36:3169–3176, 2013.(eGFR>=60) as shown below!
for calculation, please take a look at click here

PG [mmol/L]( 00min) :
PG [mmol/L](120min) :
Insulin [microU/ml] ( 00min):
Insulin [microU/ml] (120min):

RESULTS
Matsuda Index: (whole body insulin resistant: equal or lower than 2.5)

Matsuda Index corrected: [non-diabetic]
--by Urine Glucose Excretion: g/OGTT
Matsuda Index corrected: [non-diabetic with SGLT2i]
--by Urine Glucose Excretion: g/OGTT
Matsuda Index corrected: [diabetes]
--by Urine Glucose Excretion: g/OGTT
Matsuda Index corrected: [diabetes with SGLT2i]
--by Urine Glucose Excretion: g/OGTT

HOMA-IR(Matthews1985): (normal: lower or equal to 1.6, liver insulin resistant: equal or more than 2.5.)

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